Document 1807 DOCN M94A1807 TI Impact of hospital experience on HIV-disease mortality. DT 9412 AU Le R; Hogg RS; Thomson A; Strathdee SA; Schechter MT; O'Shaughnessy MV; Montaner JS; British Columbia (BC) Centre for Excellence in HIV/AIDS,; Vancouver, Canada. SO Int Conf AIDS. 1994 Aug 7-12;10(1):447 (abstract no. PD0397). Unique Identifier : AIDSLINE ICA10/94370768 AB OBJECTIVE: To assess the relationship between HIV/AIDS caseload and HIV-disease mortality in hospitals. METHODS: A population-based study was conducted using cases in the HMRI data system (Hospital Programs, B.C. Ministry of Health) from 1987-92, which had HIV/AIDS diagnostic codes (ICD-9-CM 042-044 and 795.8) on their discharge abstract. High (HEH) experienced hospitals were defined a priori as the 5 tertiary hospitals with the highest absolute number of HIV/AIDS admissions. Low experienced hospitals (LEH; n = 56) were all remaining hospitals which had HIV admissions. Logistic regression determined which of gender, age, admission type & year, ICU use, AIDS, case mix group, and resource intensity weight, predicted hospital experience and total & PCP mortality. RESULTS: A total of 4250 cases (3584 in HEH; 666 in LEH) were identified. Overall mortality rates increased in HEH from 83 per 1000 in 87/88 to 184 per 1000 in 1991/92 and remained steady in LEH at 128 per 1000 over the same interval (see figure). From 87-92, PCP mortality rates rose in both groups from 90.4 to 175 per 1000 in HEH and 138 to 229 per 1000 in LEH. Overall mortality was associated patients who had AIDS (p = 0.001), spent time in ICU (p = 0.0001), were more recently admitted (p = 0.0001), were older (p = 0.0001), received acute level care (p = 0.0001), or were admitted to HEH (p = 0.0473). PCP mortality was associated with cases from patients who spent time in ICU (p = 0.0001), were older (p = 0.0001), and received acute level care. HEH cases were more likely to be males (p = 0.0001), have longer lengths of stay (p = 0.0001), have AIDS (p = 0.0001), and AIDS-related case mix group (p = 0.0005). CONCLUSIONS: Unlike other studies, this analysis demonstrates that high experienced hospitals in the province do not consistently have lower mortality rates. This is likely due to the fact that HEH cases were more often AIDS or from an AIDS-related case mix group. We attribute the increasing mortality in the high experience hospitals to a shift in admission patterns towards sicker patients and terminal care. TABULAR DATA, SEE ABSTRACT VOLUME. DE AIDS-Related Opportunistic Infections/MORTALITY British Columbia Female *Hospital Mortality Human HIV Infections/*MORTALITY Male Pneumonia, Pneumocystis carinii/MORTALITY MEETING ABSTRACT SOURCE: National Library of Medicine. NOTICE: This material may be protected by Copyright Law (Title 17, U.S.Code).